Cure CLCN4

Scientific Meeting 2024

Did last year’s Cure CLCN4 Scientific Conference leave you inspired? We’re thrilled to announce that the momentum continues with our third annual event! Join us on 7th & 8th June 2024, in London, UK (*hybrid), for another round of ground-breaking research, enlightening discussions, and invaluable networking opportunities.

Key details

When: Friday 7th June (10:30 – 17:30 BST) & Saturday 8th June (10:15 -15:30 BST)
Where: Friends House (London, UK) (and online!). Travel information can be found here.
Organizer: Cure CLCN4
Registration: please click here to register. Registration for in-person attendance is now closed. Register for online attendance until 4th June.

Conference description

CLCN4-related neurodevelopmental condition (CLCN4-NDC) is a rare X-linked genetic disorder that leads to intellectual disability and other problems such as epilepsy, behavioural disorders, movement disorders and microcephaly. CLCN4-NDC is caused by mutations in the CLCN4 gene, which encodes the ClC-4 protein, a 2Cl-/H+ ion exchanger expressed in intracellular compartments in a wide variety of tissues, but prominently in the brain and skeletal muscle. The extent and severity of CLCN4-related condition, which has so far been reported in just over 120 individuals worldwide, is very variable, depending on the type of gene change, the gender of the affected individual, the pathophysiological impact of the genetic change and, as yet, incompletely understood factors. Overall, there is currently little understanding of the basic biology of CIC-4 and no appropriate therapeutic options.

Now in its third installment, the Cure CLCN4 Scientific Conference is set to reconvene in London, continuing its goal of providing the opportunity of the year for researchers and clinicians working on CLCN4-related condition and related areas to meet in person, network, and engage in in-depth discussions about the latest research and advancements in the field. Though short talks and panel discussions, we will explore the entire research spectrum, from fundamental animal and cellular model studies to the latest developments in clinical research, drug discovery, and precision medicine.

Conference program

See the most up-to-date list of confirmed speakers below.

Poster session

The Cure CLCN4 Scientific Conference is pleased to announce the return of the poster session, inviting PhD students and early-career researchers to present their latest work on CLCN4-related condition and related themes. This session offers a unique opportunity for emerging scientists to showcase their research, engage in valuable discussions, and receive feedback from experts in the field. To participate please submit your abstracts by 6th of May 2024. For more information please click here.